The US Treasury Department on Tuesday slapped sanctions on a German bank accused of helping Iran evade international sanctions and supporting its nuclear and missile activities.

Europaeisch-Iranische Handelsbank (EIH), based in Hamburg, has handled billions of dollars in transactions on behalf of the Iranian government and entities involved in its nuclear and missile programs, according to the Treasury Department.

The bank is also said to have previously done business with other Iranian banks already under sanctions.

“As one of Iran’s few remaining access points to the European financial system, EIH has facilitated a tremendous volume of transactions for Iranian banks previously designated for proliferation,” said Stuart Levey, Treasury undersecretary.